Chemistry Online Lectures


Principles of Chemical Science
Prof. Catherine Drennan, Dr. Elizabeth Vogel Taylor, MIT

L1 The importance of chemical principles
L2 Discovery of electron and nucleus, need for quantum mechanics
L3 Wave-particle duality of light
L4 Wave-particle duality of matter, Schrodinger equation
L5 Hydrogen atom energy levels
L6 Hydrogen atom wavefunctions (orbitals)
L7 p-orbitals
L8 Multielectron atoms and electron configurations
L9 Periodic trends
L10 Periodic trends continued; Covalent bonds
L11 Lewis structures
L12 Exceptions to Lewis structure rules; Ionic bonds
L13 Polar covalent bonds; VSEPR theory
L14 Molecular orbital theory
L15 Valence bond theory and hybridization
L16 Determining hybridization in complex molecules; Thermochemistry and bond energies/bond enthalpies
L17 Entropy and disorder
L18 Free energy and control of spontaneity
L19 Chemical equilibrium
L20 Le Chatelier's principle and applications to blood-oxygen levels
L21 Acid-base equilibrium: Is MIT water safe to drink?
L22 Chemical and biological buffers
L23 Acid-base titrations
L24 Balancing oxidation/reduction equations
L25 Electrochemical cells
L26 Chemical and biological oxidation/reduction reactions
L27 Transition metals and the treatment of lead poisoning
L28 Crystal field theory
L29 Metals in biology
L30 Magnetism and spectrochemical theory
L31 Rate laws
L32 Nuclear chemistry and elementary reactions
L33 Reaction mechanism
L34 Temperature and kinetics
L35 Enzyme catalysis
L36 Biochemistry

Thermodinamics and Kinetics
Emeritus Professors of Chemistry: Robert A. Alberty, Carl W. Garland, Irwin Oppenheim, John S. Waugh.
Professors of Chemistry: Moungi Bawendi, John M. Deutch, Robert W. Field, Robert G. Griffin, Keith A. Nelson, Robert J. Silbey, Jeffrey I. Steinfeld.
Professor of Bioengineering and Computer Science: Bruce Tidor.
Professor of Chemistry, Rice University: James L. Kinsey.
Professor of Physics, University of Illinois: Philip W. Phillips.

1 State of a system, 0th law, equation of state
2 Work, heat, first law
3 Internal energy, expansion work
4 Enthalpy
5 Adiabatic changes
6 Thermochemistry
7 Calorimetry
8 Second law
9 Entropy and the Clausius inequality
10 Entropy and irreversibility
11 Fundamental equation, absolute S, third law
12 Criteria for spontaneous change
13 Gibbs free energy
14 Multicomponent systems, chemical potential
15 Chemical equilibrium
16 Temperature, pressure and Kp
17 Equilibrium: application to drug design
18 Phase equilibria: one component
19 Clausius-Clapeyron equation
20 Phase equilibria: two components
21 Ideal solutions
22 Non-ideal solutions
23 Colligative properties
24 Introduction to statistical mechanics
25 Partition function (q) large N limit
26 Partition function (Q) many particles
27 Statistical mechanics and discrete energy levels
28 Model systems
29 Applications: chemical and phase equilibria
30 Introduction to reaction kinetics
31 Complex reactions and mechanisms
32 Steady-state and equilibrium approximations
33 Chain reactions
34 Temperature dependence, Ea, catalysis
35 Enzyme catalysis
36 Autocatalysis and oscillators

Freshman Organic Chemistry
Professor J. Michael McBride , Yale University

1. How Do You Know?
2. Force Laws, Lewis Structures and Resonance
3. Double Minima, Earnshaw's Theorem, and Plum-Puddings
4. Coping with Smallness and Scanning Probe Microscopy
5. X-Ray Diffraction
6. Seeing Bonds by Electron Difference Density
7. Quantum Mechanical Kinetic Energy
8. One-Dimensional Wave Functions
9. Chladni Figures and One-Electron Atoms
10. Reality and the Orbital Approximation
11. Orbital Correction and Plum-Pudding Molecules
12. Overlap and Atom-Pair Bonds
13. Overlap and Energy-Match
14. Checking Hybridization Theory with XH3
15. Chemical Reactivity: SOMO, HOMO, and LUMO
16. Recognizing Functional Groups
17. Reaction Analogies and Carbonyl Reactivity
18. Amide, Carboxylic Acid and Alkyl Lithium
19. Oxygen and the Chemical Revolution (Beginning to 1789)
20. Rise of the Atomic Theory (1790-1805)
21. Berzelius to Liebig and Wohler (1805-1832)
22. Radical and Type Theories (1832-1850)
23. Valence Theory and Constitutional Structure (1858)
24. Determining Chemical Structure by Isomer Counting (1869)
25. Models in 3D Space (1869-1877); Optical Isomers
26. Van't Hoff's Tetrahedral Carbon and Chirality
27. Communicating Molecular Structure in Diagrams and Words
28. Stereochemical Nomenclature; Racemization and Resolution
29. Preparing Single Enantiomers and the Mechanism of Optical Rotation
30. Esomeprazole as an Example of Drug Testing and Usage
31. Preparing Single Enantiomers and Conformational Energy
32. Stereotopicity and Baeyer Strain Theory
33. Conformational Energy and Molecular Mechanics
34. Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes
35. Understanding Molecular Structure and Energy through Standard Bonds
36. Bond Energies, the Boltzmann Factor and Entropy
37. Potential Energy Surfaces, Transition State Theory and Reaction Mechanism

Marine Chemistry
Professors Scott Doney, Bill Martin, Karen Casciotti, Meg Tivey, Dierdre Toole , MIT

7 Marine carbonate chemistry
10 Non-conservative processes in estuaries/groundwater/hydrothermal
11 Gas exchange across the air-sea interface
12 Atmospheric-ocean interaction
13 Primary production (1)
14 Primary production (2)
17 Sinking particles and remineralization (2)
18 Quantifying biogeochemical fluxes and rates
19 Early diagenesis I
20 Early diagenesis II and sediment distributions
22 P cycle
25 Anthropogenic CO2 (2)